Wenxing Chen Selected Research

Pyruvate Kinase

10/2019	Beta-elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation.
1/2019	Breaking Glucose Transporter 1/Pyruvate Kinase M2 Glycolytic Loop Is Required for Cantharidin Inhibition of Metastasis in Highly Metastatic Breast Cancer.

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Wenxing Chen Research Topics

Disease

33	Neoplasms (Cancer) 12/2024 - 08/2010
16	Neoplasm Metastasis (Metastasis) 04/2024 - 01/2011
10	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2012
8	Melanoma (Melanoma, Malignant) 03/2024 - 01/2011
4	Carcinogenesis 02/2020 - 07/2014
3	Hypoxia (Hypoxemia) 03/2024 - 01/2012
3	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2013 - 01/2012
2	Colonic Neoplasms (Colon Cancer) 01/2023 - 01/2021
2	Pathologic Processes 11/2021 - 01/2020
2	Carcinoma (Carcinomatosis) 01/2021 - 07/2014
2	Body Weight (Weight, Body) 01/2020 - 01/2019
2	Chronic Hepatitis (Chronic Active Hepatitis) 01/2019 - 09/2013
2	Triple Negative Breast Neoplasms 01/2018 - 01/2015
2	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2011 - 03/2011
1	Skin Diseases (Skin Disease) 03/2024
1	Stomach Neoplasms (Stomach Cancer) 12/2023
1	Dysbiosis 11/2023
1	Necrotizing Enterocolitis 11/2023
1	Chronic Obstructive Pulmonary Disease (COPD) 01/2023
1	Poisoning 11/2021
1	Skin Neoplasms (Skin Cancer) 07/2020
1	Granuloma 01/2020
1	Colitis 01/2020
1	Pharyngitis (Sore Throat) 01/2020
1	Colorectal Neoplasms (Colorectal Cancer) 11/2019

Drug/Important Bio-Agent (IBA)

9	cryptotanshinoneIBA 03/2024 - 08/2010
6	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 03/2024 - 08/2010
5	AntioxidantsIBA 01/2023 - 03/2011
4	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2015
3	EnzymesIBA 01/2018 - 07/2014
3	TOR Serine-Threonine KinasesIBA 01/2017 - 08/2010
3	GlycosaminoglycansIBA 12/2015 - 01/2013
3	IntegrinsIBA 12/2015 - 01/2012
3	Matrix Metalloproteinases (MMPs)IBA 12/2015 - 01/2013
2	Glucose (Dextrose)FDA LinkGeneric 03/2024 - 01/2021
2	Therapeutic UsesIBA 03/2024 - 01/2020
2	Transcription Factors (Transcription Factor)IBA 01/2023 - 05/2012
2	Transient Receptor Potential ChannelsIBA 12/2022 - 09/2016
2	tanshinoneIBA 01/2022 - 01/2021
2	MicroRNAs (MicroRNA)IBA 01/2022 - 02/2020
2	Estrogen ReceptorsIBA 01/2021 - 01/2012
2	Estrogens (Estrogen)FDA Link 01/2021 - 01/2012
2	Acetates (Acetic Acid Esters)FDA Link 07/2020 - 07/2014
2	anthraceneIBA 07/2020 - 07/2014
2	LycopeneIBA 01/2020 - 07/2014
2	CarcinogensIBA 01/2020 - 07/2014
2	beta-elemeneIBA 10/2019 - 04/2011
2	Pyruvate KinaseIBA 10/2019 - 01/2019
2	elemeneIBA 10/2019 - 04/2011
2	Mechanistic Target of Rapamycin Complex 1IBA 01/2019 - 01/2017
2	Retinoblastoma ProteinIBA 01/2018 - 08/2010
2	Cyclin D1IBA 01/2018 - 08/2010
2	diallyl trisulfideIBA 01/2018 - 01/2015
2	Small Interfering RNA (siRNA)IBA 01/2018 - 01/2017
2	Angiogenesis InhibitorsIBA 10/2016 - 01/2011
2	Messenger RNA (mRNA)IBA 10/2016 - 01/2015
2	Polysaccharides (Glycans)IBA 12/2015 - 01/2015
2	Volatile Oils (Essential Oils)IBA 06/2013 - 01/2011
2	CaspasesIBA 05/2012 - 11/2010
2	CadmiumIBA 04/2011 - 03/2011
1	nintedanibIBA 12/2024
1	Adenosine Monophosphate (AMP)IBA 03/2024
1	PhosphofructokinasesIBA 03/2024
1	Protein Kinases (Protein Kinase)IBA 03/2024
1	Capsaicin (Zostrix)FDA Link 12/2023
1	16S Ribosomal RNAIBA 12/2023
1	CobaltIBA 01/2023
1	condensin complexes (condensin)IBA 01/2023
1	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/2023
1	Fluorouracil (Carac)FDA LinkGeneric 01/2023
1	Glutathione (Reduced Glutathione)IBA 01/2023
1	Sincalide FDA Link 01/2023
1	Actin Depolymerizing Factors (Cofilins)IBA 12/2022
1	CortactinIBA 12/2022
1	baicalinIBA 12/2022
1	kaempferolIBA 09/2022
1	lipid transfer protein (glycolipid transfer protein)IBA 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 11/2021
1	ChlorineIBA 11/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020
1	Lipocalin-2IBA 01/2020
1	rheinIBA 01/2020
1	Analgesics (Analgesic Drugs)IBA 01/2020
1	purineIBA 01/2020
1	Dextran SulfateIBA 01/2020
1	CytokinesIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	Uric Acid (Urate)IBA 01/2020
1	Dietary CalciumIBA 11/2019
1	Vitamin D FDA LinkGeneric 11/2019

Therapy/Procedure

18	Therapeutics 03/2024 - 01/2013
3	Drug Therapy (Chemotherapy) 01/2023 - 01/2021
3	Chemoprevention 07/2020 - 10/2016
2	Immunotherapy 01/2022 - 01/2021
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 01/2019 - 09/2013
1	Fecal Microbiota Transplantation 12/2023
1	Traditional Medicine (Folk Remedies) 07/2020